Fatty acid derivatives
Hence, they become essential fatty acids: Linoleic acid: C 18:2 (9,12) = omega 6 (precurosor of arachidonic acid) Maximum in safflower oil

Unsaturated fatty acid derivatives play a critically important role in virtually every life form. Monoenoic acid (C 18:1) was more inhibitory than saturated fatty acid, but was less active than dienoic derivatives (C 18:2).

Peter H. Buist, in Comprehensive Natural Products II, 2010. Fatty acid derivatives are broad-spectrum anticonvulsant drugs, which are effective against most types of seizures.


Our data indicate that C 12 (lauric acid) is the most inhibitory saturated fatty acid against gram-positive organisms. These beneficial results favorably compare to prior agents utilized for treating inflammation, autoimmune disorders, and/or pain. 1.02.1 Introduction.

The disclosed fatty acid derivatives have increased activity, lower toxicity, greater stability, and longer half-life in a relevant rat model.

They can be used to treat absence seizures, tonic-clonic seizures, juvenile myoclonic epilepsy and complex partial seizures.

Other unsaturated compounds were less active than C 18:2. C 18:1 (9) = Oleic acid (omega 9) B. Polyunsaturated fatty acid (PUFA): Humans lack the ability to introduce double bonds in fatty acids beyond carbons 9 and 10, as counted from the carboxylic acid side.

Contact

 

LINE Contact